Sigma-Aldrich Corporation (Nasdaq:SIAL) will hold its quarterly conference call to discuss second quarter results on July 22, 2010 at 11:00 AM Eastern Time (10:00 AM Central Time).

Date: July 22, 2010
Time: 10:00 AM CT

Toll Free: 877-852-6573
International: 719-325-4822
Passcode: 2694832

Webcast and slide presentation available via Internet:
http://investor.sigmaaldrich.com/

Replay Information:

Toll Free: 888-203-1112

International: 719-457-0820

Passcode: 2694832

Schedule this webcast into MS-Outlook calendar (click open when prompted): http://apps.shareholder.com/PNWOutlook/t.aspx?m=40171&k=DB30B762

About Sigma-Aldrich: Sigma-Aldrich is a leading Life Science and High Technology company. Its biochemical and organic chemical products and kits are used in scientific research, including genomic and proteomic research, biotechnology, pharmaceutical development and as key components in pharmaceutical, diagnostic and other high technology manufacturing. The Company has customers in life science companies, university and government institutions, hospitals, and in industry. Over one million scientists and technologists use its products. Sigma-Aldrich operates in 38 countries and has 7,600 employees providing excellent service worldwide. Sigma-Aldrich is committed to Accelerating Customer Success through Innovation and Leadership in Life Science, High Technology and Service. For more information about Sigma-Aldrich, please visit its award-winning Web site at http://www.sigma-aldrich.com.

This news release was distributed by GlobeNewswire, www.globenewswire.com